Kaplaushenko A. Synthesis, structure and biological activity of 4-mono- and 4,5-disubstituted 1,2,4-triazol-3-thione derivatives

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0512U000491

Thesis Registration Form

0512U000491.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

12-06-2012

Specialized Academic Board

Д 17.600.03

Zaporizhzhya State Medical University

Essay

On the basis of self-minded synthesis of more than 350 compounds of raw of 4-mono- and 4,5-disubstituted 1,2,4-triazol-3-thione and study of their biological activity has solved important scientific problem of pharmacy and medicine - there was composed potential original low toxic neuroprotective medicine with adaptogenous properties "Thiometrizole" of antioxidant and antiischemic mechanism of action for which is scientifically grounded usage in prevention, first aid and therapy of the diseases connecting with dysfunctions of blood vessel supplying the brain and also for increasing of general adaptive opportunities of the organism.

Read more

Files

aref.doc

dis.docx

Similar theses

0523U100273

Lozynskyi Andrii V.

Polyfunctional condensed and non-condensed thiazole/thiazolidinone derivatives: directed synthesis, physicochemical properties and biological activity

0523U100081

Safonov Andrii A.

Синтез, перетворення, фізико-хімічні і біологічні властивості похідних 1,2,4-триазолу, які містять тіофен-2-ілметильний замісник

0523U100030

Bihdan Oleksii A.

Synthesis, chemical modification and biological properties of 3-, 4, 5-trisubstituted-1,2,4-triazole-3-thions

0521U101625

Borodina Nataliia Valerivna

Pharmacognostic study of willow plants and creation of medicines based on them. Qualifying scientific work on the rights of the manuscript

0421U102935

Anosova Liydmila Sergееvna

Chemical and toxicological study of clopidogrel