Nalotova O. Essential hypertension, associated with insulin resistance: a ground of the tactical going to pharmacotherapy

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0512U000590

Applicant for

Specialization

  • 14.01.11 - Кардіологія

31-05-2012

Specialized Academic Board

Д 11.600.05

Essay

Object of research - insulin resistance of patients with arterial hypertension of second stage; a purpose is a substantiate appropriateness of including of metabolic drugs in the structure of base drugs therapy of patients with arterial hypertension of second stage, associated with insulin resistance; research methods are clinical-instrumental, laboratory, instrumental, computer statistical analysis; novelty - on the basis of clinical research the features of clinical picture are analysed, flow, changes of exchange of carbonhydratess, lipid, state of sympathic and renin-angiotenzin systems, dilatation function of endothelium of arteries, appropriateness of the use is grounded, efficiency is appraised, the bearableness and safety is certain, quality of life at application of combination of metabolic drugs (metforminum+thyotriazolinum) is analysed in composition a base antihypertensive pharmacotherapy for patients with arterial hypertension of second stage associated with insulin resistance; results - clinical research allowed to improve pathogenethic therapy of arterial hypertension associated with insulin resistance by including of metabolic drugs in the strucrure of base antihypertensive pharmacotherapy; it is introduced to medical practice, educational process; an area is medicine.

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