Voznyuk V. Mechanisms of formation of hypocoagulation and hypercoagulation condition as manifestations of imbalance of primary hеmostasis in hematological patients.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0513U000051

Applicant for

Specialization

  • 14.01.31 - Гематологія та трансфузіологія

26-12-2012

Specialized Academic Board

Д 26.612.01

State Institution "Institute of Hematology and Transfusiology NAMS Ukraine"

Essay

Specific links between the factors of peripheral hemodynamic and primary hemostasis have been identified and studied. The relation of the nature of interaction of hemodynamic and hemostatic factors to the specifics of a clinical course of hematological diseases was confirmed. The efficiency of concurrent use of indices of endothelial vasodilatation and mechanosensitivity of endothelium allowing their use as prognostic criteria for the formation of prothrombotic or prohemorhragic orientation of reactions of primary hemostasis was demonstrated.

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