Konstantin R. Hypertrophic cardiomyopathy : the problems of diagnostic and treatment

The cohort study comprised 235 pts, who were consulted and treated at the National Institute of Cardiovascular Surgery Academy of Medical Sciences of Ukraine, Kyiv, Ukraine. All pts with a non-obstructive form of the disease underwent drug therapy. Сonsecutive pts with a drug refractory form were treated invasively and received the biggest part of our attention. This study demonstrates that, in patients with drug refractory symptomatic obstructive HCMP, surgical myectomy, transcoronary alcohol septal ablation and DDD pacing are equally effective at reducing left ventricular out of tract obstruction and lead to similar subjective improvements in functional capacity. Surgical myectomy, however, was more effective in improving NYHA functional class. Surgical methods of treatment are preferable in cases of evident SPG and high rate of mitral regurgitation. Thus, according to the received findings we can say that surgery remains the gold standard of HOCM treatment, but successful use of alternative methods of treatment such as DDD pacing and alcohol ablation is also successfully can be applied. Thus, according to obtained results we can say that every method of treatment has its clearly defined indications. We had good results with patients, who received precise indications for a certain method of treatment.