Mishchenko L. Systemic inflammation and metabolic cardiovascular risk factors as determinants of progression of target organ damage in patients with essential hypertension

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0513U001141

Thesis Registration Form

0513U001141.pdf

Applicant for

Specialization

  • 14.01.11 - Кардіологія

29-10-2013

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The thesis established role of systemic inflammation and disorders of carbohydrate and purine metabolism as significant factors of progression of essential hypertension (EH) and target organ damage. The prognostic role of CRP in the development and progression of left ventricular hypertrophy, carotid intima-media thickening and renal function deterioration was identified in hypertensive patients. It is shown that cardio- and nephroprotective effects of losartan, valsartan and perindopril associated with the decrease in the activity of systemic inflammation, improve insulin sensitivity and regression microalbumiuria.

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Files

Автореферат_Міщенко.doc

Дисертація_Міщенко.doc

Дисертація_Міщенко.doc

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