Salmanov A. Epidemiological surveillance for postoperative purulent surgical wound infections induced by pathogens resistant to antibiotics

The thesis is devoted to the improvement of the epidemiological surveillance system , based on the study of the main characteristics of the epidemic process of the postoperative purulent surgical wound infections induced by the pathogens resistant to antibiotics. Study was performed on the data from 253207 patients hospitalized during 2008-2012 in 97 surgical hospitals in Ukraine. The main causative agents of these diseases belong to S. aureus, E. faecalis, E. coli, Enterobacter spp. and P. aeruginosa . Of these, 70.7 % are resistant to at least one antibiotic. Multiresistant strains averaged 34.4%, including S.aureus - 25,9%, E. faecalis - 37,0%, E.coli - 26,3%, Enterobacter spp. - 30.3% and P. aeruginosa - 50,2%. A direct relationship was observed between the incidence of purulent surgical wound infection progression and resistance of the pathogens. The system of surveillance is suggested, which is based on the epidemiological diagnosis of postoperative purulent surgical wound infections and monitoring of resistance of pathogens derived from patients, staff and epidemiologicaly significant environmental objects in the surgical setting.