Svyrydov М. Complex differentiated surgical treatment of purulent-necrotic lesions of foot among patients with diabetes mellitus

The study object is a wounding process in purulo-necrotic forms of diabetic foot syndrome of different spreading degrees; the purpose is to improve the effectiveness of surgical treatment of patients with purulo-necrotic forms of diabetic foot syndrome by development of the differential approach to the optimal terms option, kinds and measures of reconstructive operations based on the complex evaluation of individual pathogenetic and pathomorphologic peculiarities of wounding process duration; the methods are: clinical, cytological, radioimmunologic, morphologic, immunohistochemical, statistical; the novelty is was developed a wound therapy system in patients with diabetic foot syndrome, it was also proposed a clear algorithm of differential surgical treatment; it was established an individual character of wounding process duration with peculiarities of cellular reactivity, patho- and morphogenesis; the possibilities of the newest technologies and surgical methods usage on the final period of surgical treatment basing on the implementation of coefficients of the histochemical results of wounding process duration from the scientific point of view; the results are: the implementation of original methods of surgical treatment using the newest biotechnologies allowed to minimize the traumatism of extremity tissues during the reconstructive interferences, to improve the direct, delayed and functional treatment results as well as to shorten a period of medical and social rehabilitation; It is inculcated - in medical practice, in an educational process; Sphere - medical practice.