Paustovsky Y. Hygienic Assessment of Methyl Tertiary-Butyl Ether as a Global Environmental Pollutant and Molecular Genetic Mechanisms of its Action in a Living Organism.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0516U000051

Thesis Registration Form

0516U000051.pdf

Applicant for

Specialization

  • 14.02.01 - Гігієна

05-01-2016

Specialized Academic Board

Д 26.003.01

Essay

The dissertation is devoted to important current topic in the field of preventive medicine, namely: specific biological action of a methyl tertiary-butyl ether (MTBE) as well as prevention and early detection of MTBE harmful impact on human health using the molecular genetic biomarkers. It was determined that MTBE exerts embryotoxic, teratogenic, gonadotox-ic and other effects on a living organism. The following molecular genetic mechanisms are underlying the MTBE damaging effect: changes in gene expression levels of key circadian factors and protein kinases. The package of scientifically valid measures was developed and introduced into the health care practice in order to reduce the levels of hazardous chemicals in the environment, and to prevent their harmful effect on workers and the general population.

Read more

Files

act_vpr.pdf

aref.doc

aref.doc

dis.doc

Similar theses

0521U101962

Zazulyak Tetyana Stepanivna

Improvement and harmonization of the system of hygienic regulations on the permissible concentration of chemical substances in workplace air with the European legislative framework in the case of pharmaceutical production

0521U101966

Andrushchenko Tetyana Anatoliivna

Genetic markers of DNA repair effectiveness under the influence of occupational factors

0421U000101

Kovalchuk Mariia Petrivna

Scientific rationale of measures for prevention of negative influence of outdoorair on the incidence of bronchial asthma in children of Kyiv

0421U000092

Chaika Anna Volodymyrivna

Hygienic assessment of the conditions of placement and operation of health care facilities built into residential buildings

0421U000093

Avdiievska Olena Heorhiivna

Hygienic assessment of the conditions for the formation of a health-preserving environment in the families of students of general secondary education