Goncharenko V. Hyperplastic processes of endometrium (prediction, diagnosis, treatment and rehabilitation)

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0517U000157

Thesis Registration Form

0517U000157.pdf

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

02-03-2017

Specialized Academic Board

Д 26.003.03

Essay

The dissertation is devoted to the optimization of diagnosis and treatment of hyperplastic processes of endometrium by using modern diagnostic techniques. The thesis includes the clinical and statistical analysis, specific social and medical risk factors for hyperplastic processes of endometrium by three age groups; their separate and combined significance has been detected. With due account for the data of clinical and statistical analysis and instrumental and laboratory research has been developed and proved a new diagnostic diagnostics algorithm of endometrial pathology among the women through using modern functional and minimally invasive techniques. By means of immunohistochemical studies has been investigated the role of chronic endometritis and of the intratissual APUD-system in the genesis of hyperplastic processes of endometrium, and new pathogenesis links of this disease have been detected. Based on the clinical and instrumental examination and pathomorphological research has been developed and introduced into clinical practice the differentiated algorithm of staging diagnostic and therapeutic measures for optimization of medical care for patients with hyperplastic processes of endometrium. Applying a differentiated approach improved the treatment results of simple endometrial hyperplasia without atypia in the reproductive age by 24.9%, in premenopausal age by 20.9%, of complex endometrial hyperplasia without atypia in the reproductive age by 16.4% in premenopausal age by 19.4% . It was proved, that monopolar hysteroscopic or radio-frequency endometrial ablation can be recommended to the patients with non-atypical endometrial hyperplasia forms as alternative to hormonal treatment or a hysterectomy. It was detected, that the effectiveness of monopolar hysteroscopic endometrial ablation by women with non-atypical forms of endometrial hyperplasia makes 87.8%. Efficiency of monopolar hysteroscopic endometrial ablation by women in postmenopausal age with non-atypical forms of endometrial hyperplasia makes 95,0%.

Read more

Files

Гончаренко-дисертація.pdf

автореферат от В.А--Гончаренко Титул друк.doc

автореферат от В.А--Гончаренко автореферат.doc

д2--disser etalon--0 ТИТУЛ 1.docx

д2--disser etalon--1 обзор с апоптозом 16-56.docx

д2--disser etalon--10 ВИСНОВКИ 352 -359.docx

д2--disser etalon--11 список литературі єталон 360.docx

д2--disser etalon--2 КЛІНІЧНА ХАРАКТЕРИСТИКА ХВОРИХ 57-72.docx

д2--disser etalon--3 1 РОЗДІЛ 3 73-88 общий и репродуктивний вік (1).docx

д2--disser etalon--3 2 Глава 3,2 89-105пременопаузальний вік (1).docx

д2--disser etalon--3 3 Глава 3-3 106-122 постменопаузальний вік новые цифры (2).docx

д2--disser etalon--4 лава 4 патоморфология 123 - 198.docx

д2--disser etalon--5 розділ 199-213 микробіологія и иммунологія новая (1)888888888888888888888888888.docx

д2--disser etalon--6 роздил 214-226 гормоны чистовик.docx

д2--disser etalon--7 розділ 7 227-242 чистовик Глава УЗД и еластографія.docx

д2--disser etalon--8 репродуктивный лечение чистовик 243-273.docx

д2--disser etalon--8.4 .хирургічне лечение репрод пременопаузальное 274-293.docx

д2--disser etalon--8.5 Глава постменопаузальній лечение оперативное 294-312.docx

д2--disser etalon--9 УЗАГАЛЬНЕННЯ 313-351.docx0 (1).docx

Similar theses

0424U000004

Oksana M. Nepyivoda

Programme for the Management of Pregnant Women Medication Safety

0523U100264

Olha M. Proshchenko

HYSTERECTOMY DURING THE MENOPAUSAL TRANSITION. POSTOPERATIVE REHABILITATION PROGRAM

0523U100199

Olena Кrotik

Reproductive health of women against the background of sexually transmitted infections. Qualifying scientific work on manuscript rights

0523U100181

Oleg O. Berestovyj

Дисертаційна робота присвячена підвищення ефективності лікування безпліддя різного ґенезу у подружніх парах на основі вивчення нових аспектів патогенезу жіночого безпліддя, а також удосконалення та впровадження алгоритму діагностичних, лікувально-профілактичних та прогностичних заходів.

0523U100145

Oleg N. Ishchak

Reproductive health of women after the ovarian apoplexy. – Qualified scientific work on the rights of the manuscript