In the dissertation, it was performed an integrative clinical-psychopathological, psychometric, and psychodiagnostic examination of 585 patients with depressive disorders, who had been divided on 3 groups: emigrants (196 persons), re-emigrants (191 persons), and non-emigrants (198 persons). In each of these groups 3 subgroups of patients with depressions of psychogenic, endogenous, and organic genesis were defined. It was found out that in genesis of depressive disorders in emigrants and re-emigrants an important role belonged to social-stress factors, which were casual in psychogenic depressions, triggering relapse of depression in endogenous depressions, and activating psychosomatic mechanisms in organic ones. In emigrants these factors included: a physically or psychologically hard work (76.0 %), a language barrier (64.8 %), an illegal employment (46.9 %), loneliness (44.4 %), difficulties with employment (36.9 %), and problems with relatives in Ukraine (17.3 %). In re-emigrants the genesis of depressive disorders were connected with other factors: impossibility to employ (74.3 %), financial problems (70.7 %), problems with adaptation to new social and everyday life conditions (69.6 %), and family disadaptation (43.3 %). It was found out that in clinical appearance of depressive disorders a significant role belonged to anxious-depressive affect in emigrants and to sadness affect in re-emigrants. In emigrants the leading types of affect were: anxious-depressive (41.2 %) and sadness (35.3 %) ones in psychogenic depression; apathic (33.9 %) and anxious-depressive (33.3 %) ones in organic depression; sadness (48.5 %) and anxious-depressive (33.3 %) ones in endogenous depressions. In re-emigrants sadness (53.7 %) and anxious-depressive (19.4 %) affects prevailed in psychogenic depressions; in organic and endogenous depressions there was predomination of apathic (54.1 % and 49.2 % respectively) and sadness (21.3 % and 20.6 % respectively) affects. On the basis of results of the integrated investigation, it was worked out a program of a comprehensive therapy and rehabilitation for emigrants and re-emigrants with depressions of different genesis. The developed system is integrated, differentiated, and has four steps; it includes a differentiated application of antidepressants and other psychotropic medications, as well as methods of psychotherapy and psychosocial rehabilitation (rationale, family, cognitive-behavioral, and group psychotherapy; autogenous training and psychoeducation).
