Borisova I. The features of etiology and clinics, factors of prognosis and treatment optimization of pneumonia in patients with immunity disorders on a background of oncohematological pathology.

Researched object: pneumonia, associated with the damage to the immune system at the background of hematologic pathology. Mehta Methodology of progress: head-on, clinical, laboratory and instrumental methods - for diagnostics and differential diagnosis of pneumonia and nosological formation of hematologic pickup; vivchennya anamnesis going on hematologic oncology; klіnіchny monitoring hvoryh for the designation of specialties perebіgu pneumonia; microbiological and bacteriological methods - for the identification of the main zbudniki pneumonia (ZP) in a harkotinni in the central broncho-alveolar lavage (BAL); Instruments - Fibrobronchoscopia (FBS) for rydinnya Ridini BAL; imunofermental - for the assessment I will become a clinine and humoral immunity; For the processing of the results of the study and construction of the prediction model, the mathematical mathematical and statistical methods are used. Naukova novelty: The upper frequency of the frequency of the disorder is determined, the frequency of occurrence of the frequency of the fatal conditions of the pneumonia in diseases of the immune system on the basis of hematologic pathology. Viznacheni factor rhiziku, scum obumovlyuyut viniknennya pneumonia in the apels of pushenenny іmunіetu. On the basis of the complex of clinical laboratories, roscrites, special clinical pictures and treatment of such pneumonia, a proprietary algorithm of diagnostic diagnosis of pneumonia - pneumonia in patients with a background hematological pathology is prescribed. First of all, the main ZP and their resistance to antibacterial drugs and microorganisms are especially pneumatic. The optimality of the antibacterial therapy (ABT) pneumonia and vivchen factors, which interfere with the design of the mono combination of ABT, is prescribed. First of all, mozhnivst zastosovanna іnomomododulyuyu терап therapy і pneumonia, associated with pushenenny іmunіtetu on the background hematologic pathology, that is prescribed by uskonalenya schema lіkuvannya. On pіdstavі complex pokaznikіv klіnіko-laboratory pokaznikіv viznacheno factors scho obumovlyuyut tyazhkіst klіnіchnogo perebіgu pnevmonії i vstanovleno nezalezhnі predictor viniknennya fatal naslіdku pnevmonії (PNP), resting rozrobleno ically mathematical model predicts FNP. An analysis of the situation was carried out on the model for predicting the prevalence of pneumonia for a private modifying of the illumination of the city. Naukova novelty otrimanih results_v pіdtverdzhena 5 state patents of Ukraine.