Tsekhmistrenko O. Biotechnology of production and use of probiotics with nanoparticles of selenium and cerium dioxide in poultry.

The thesis deals with the the development of biotechnology of production and use of nanoparticles of metalloids (selenium) and metal oxides (cerium dioxide) in poultry farming. The technology of obtaining nanopreparations by means of bacterial synthesis and as a part of the micellar particles stabilized by citrate is developed. The created nanoparticles are analogs of natural compounds of Selenium and Cerium and serve as a source of their non-toxic, soluble and easily accessible form. Qualification work is devoted to the design of new preparations of cerium and selenium nanoparticles, establishing their optimal dosage for different species of poultry, testing the effectiveness of their action on the correction of adaptive systems of poultry in postnatal ontogenesis in production conditions and the impact of developed compounds on poultry.