Rudenko S. Surgical treatment of mitral regurgitation of ischemic genesis

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0521U101619

Applicant for

Specialization

  • 14.01.04 - Серцево-судинна хірургія

12-05-2021

Specialized Academic Board

Д 17.600.01

State Institution “Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine”

Essay

The data obtained as a result of the study allowed to improve the indications for surgical treatment of mitral regurgitation of ischemic origin and to justify the choice of surgical correction. As a result of the dissertation, theoretical provisions covering the aspects of the spread, pathogenesis, clinic of mitral regurgitation of ischemic genesis were obtained, which allowed to scientifically substantiate the methods of improving the diagnosis and treatment of this disease. New theoretical positions have been formed that the main component of the pathogenesis of MN in coronary heart disease is postischemic remodeling of the left ventricle, which is manifested by a symmetrical increase in LV volume in chronic coronary syndrome without MI in the anamnesis or asymmetric changes in shape and volume in MI and accompanied by dilution and increasing the diameter of the fibrous ring MK. In acute coronary syndrome, the main causes of MN are heart attack and rupture of the papillary muscles, as well as asymmetric changes in the shape of the left ventricle due to dyskinesia of the part of the wall with attached papillary muscles. Among all patients, dilatation of the mitral valve ring was detected in 35.9% of cases, displacement of the papillary muscles - in 37.0%, detachment of the mitral valve chord - in 23.3%, infarction of the papillary muscles of the left ventricle - in 2, 4%, separation of the papillary muscles of the left ventricle - in 1.4% of cases.

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