Yukhimenko L. Systemic interaction of brain and cardiovascular system as a basis of human individual and typological paculiarities.

Dissertation work presents a solution of a scientific problem on the individual and typological paculiarities of systemic interaction of human brain and cardiovascular system during mental and physical gravitational loading (orthostatic and anti-orthostatic). Following the paradigm of autoregulation as a way of achieving an integral, optimal, adaptive result and the theory of functional systems, regarding to the existence of orderly relationships between systems of an organism, we conducted the complex comparative studies of mechanisms of the functional integration of brain and cardiovascular system (CVS) in healthy people and in individuals with hearing deprivation. The study establishes that as physical (gravitational), as mental loading are accompanied with complex restructuring in functioning of CVS (central, cerebral hemodynamic, heart rate) and brain (electroencephalographic patterns, evoked potentials), electrical skin activity, occurring in accordance to individual and typological properties of the human higher nervous activity (HNA). The research shows that evoked cognitive brain activity of people with a high level of functional mobility, power and balance of nervous processes in relation to individuals with its lower gradations, is accompanied with higher rate of nervous impulses’ transmission, demonstrating more powerful potential of neurophysiological and autonomic functions, which is mobilized to process stimuli. We investigate peculiarities of the brain and CVS functioning in conditions of mental activity of people with different status of hearing function, which indicate on the limitations of speed processes in nervous chains, reduce of efficiency of brain activity and tension of mechanisms of its autonomic support in deaf people.