Rozhkovs'ka N. Perinatal care in pregnancy complicated by placental insufficiency

Research Object: pregnant women fetus, newborn, blood, urine, placenta, vaginal excretions. Research Aim: rise off effectiveness of perinatal care guard by dint of elaboration of differentiated apporoaches to prognostication, to diagnostics, to prophylaxy and to violations correction of adaptation mechanisms in mother-placenta-fetus system attached to chronic placental insufficiency in dependenceon pathogenic mechanisms of its development. Research Methods and apparatus: clinical, biophysical, biochemical, immunological, immunoenzime, radioimmune, immunoflourescental, bacteriological, morphohystological; photometer " Multiscan MCC/340", microscopes, fetal monitors, hemocoagulographe, centrifuges, ultrasound scanners, ALIB-1, gamma-chamber. Theoretical results and novelty: proved pathogenic role of hyperproduction of autoantibodies to cardiolipin and phosphatidilserin and human chorionic gonadotropin and also reactivation of herpesviral infection min the making of placental insufficiency and fetal growt h restriction. Practical results and novelty: are worked up the new differentiated methods of treatment in pregnant women with placental insufficiency syndrome of with use ticlid, normal human intravenous immunoglobulin and photohemotherapy, and also actovegin is proved their effectiveness in comparison with traditional therapy. Inculcation Degree: publication in magazines and collections, edition of educational manual, appearance on professional conferemces, congresses, methodical recommendations, use in medical founding and scientifically-pedagogic work. Inculcation Effectiviness: rise of effectiviness of perinatal care, decreasing of perinatal morbidity and mortality; deepening of knowledges in relation to pathogenesis of placental insufficiency and care of authority of hidh risk-pregnancy. Use Sphere: obstetrics, perinatology, neоnatology.