Sliusariev M. Surgical correction of primary and secondary volumetric asymmetry of the mammary glands

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0820U100441

Applicant for

Specialization

  • 222 - Медицина

25-11-2020

Specialized Academic Board

ДФ 26.003.015

Bogomolets National Medical University

Essay

Materials and methods. The study included 70 women aged 29 to 58 years, an average of 42.31 ± 0.97 years, subject to surgical treatment (mastectomy) for malignant breast cancer, not exceeding 3 cm in diameter. The volume of the breast to be removed was measured before the operation by its own method with the aid of the developed instrument and the Kuklin method and after the operation by the method of fluid displacement (MFD) - Archimedes' method, which was considered the standard. The absolute difference in the values (ADV) and the relative difference in the values (RDV) of the measurement breast volume by the own method and the Kuklin method in relation to the MFD were calculated. Discriptive statistics, comparison of mean (the Mann-Whitney U test), linear regression analysis were performed by the IBM SPSS Statistics 22. Results. According to the MFD data, the volume of the breast was 82-978 ml, an average of 363.0 ± 24.7 ml, according to the own method and the Kuklin method, 85 - 960 ml and 100 - 920 ml, an average of 360.6 ± 24.3 ml and 353.3 ± 23.3 ml. respectively, p> 0.05. The average value of ADV according to the method of Kuklin was 29.9 ± 1.5 ml (5 - 61 ml), by own method - 10.3 ± 0.47 ml (3 - 20 ml), p = 0.001. The average value of RDV according to the method of Kuklin was 9.84 ± 0.6% (1.7-31.6%,), according to the own method - 3.4 ± 0.2% (1.3-12.6%), p = 0.001. The rate of RDV less than 5% according to the method of Kuklin was 10.0%, by own method - 87.1%. The frequency of RDV more than 5% according to the method of Kuklin was 90.0% (mean volume of the breast 31.1 ± 1.5 ml), according to the own method - 12.9% (average volume of the breast 11.2 ± 0.7 ml), p = 0.001. Conclusions. 1. The developed method for determining the volume of the breast provides a high measurement accuracy: the RDV rate of less than 5% is 87.1%. 2. The developed method more accurately estimates the volume of breast than the standard method (Kuklin): the average value of ADV is 10.3 ± 0.47 ml versus 29.9 ± 1.5 ml, p = 0.001 and RDV - 3.4 ± 0.2 % vs. 9.8.4 ± 0.6%, p = 0.001, respectively.

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