Chaika M. Pathogenetic and pathomorphological aspects of acute cholecystitis and its complications diagnosis and surgical treatment

The thesis proposes an improved classification of AC taking into account the etiology, pathogenesis, combinations and complications of biliary pathology. Special clinical forms of AC are furnished, in which conservative therapy is ineffective due to the progression of the destructive process (enzymatic, emphysematous, vascular, post-traumatic forms of AC). The names of Opie syndrome, Bartolini-Bouvere-Mondor syndrome are proposed, which have many synonyms in the modern world literature. Microbiological studies of aerobic and anaerobic microflora were performed and antibiotic selective sensitivity was determined. Methods of pathomorphological studies to detect immuno-allergic, vascular and other features of destructive forms of AC were improved. The implementation of research results in practice solves an important scientific issue, namely expanding knowledge about AC and increasing the effectiveness of conservative and surgical tactics of patients with various forms of AC treatment.