Fito I. "Development of compositions and technologies of sprays for the treatment of respiratory diseases based on extracts of Iceland moss and eucalyptus"

The dissertation is devoted to the creation of new drugs for the treatment of diseases of the upper respiratory tract on the basis of moss and eucalyptus. The paper summarizes the data on the treatment of diseases of the upper respiratory tract (URT) in Ukraine, as well as on the current classification and state of treatment of these diseases. It is established that for their treatment drugs of four groups according to anatomical-therapeutic-chemical (ATX) classification are used. The data of literature sources on the objects of research were analyzed and systematized: Eucalyptus globulus та Cetraria islandica, as a promising raw material for the creation of new drugs. The botanical characteristics, chemical composition, application of raw materials Eucalyptus globulus and Cetraria islandica are given. The processed literature sources shed light on the expediency of using medicinal plant raw materials (MPR) of the studied plants for the development of new drugs for the treatment of URT diseases. Methods of identification using thin-layer (TLC), gas (GC) and high-performance liquid (HPLC) chromatography and quantitative detection of biologically active substances (BAS) using spectrophotometric (SF) and gravimetric methods in medicinal plant raw materials (LCTs) are described. preparations. These methods, respectively, determine the presence and quantitative content of essential oil and its components, chlorophylls, phenolic compounds, polysaccharides etc.