Umarov U. Phytochemical study of products of complex processing of anise ordinary

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0821U102660

Applicant for

Specialization

  • 226 - Фармація, промислова фармація

09-11-2021

Specialized Academic Board

ДФ 64.605.034

National University of Pharmacy

Essay

The thesis is devoted to phytochemical research of products of complex processing of anise, obtaining of drug, development of methods of quality control on medicinal plant raw material, drug and dosage form. Polysaccharides, organic acids, amino acids, hydroxycinnamic acids, flavonoids, chlorophylls and carotenoids were detected using classical and modern instrumental methods of analysis in the objects of study (herb, fruits and meal of anise fruits). According to the SPhU, morphological and anatomical diagnostic features, as well as numerical and technological parameters of anise herb have been established. The QCM project "Pimpinella anisum herb" is developed. 5 batches of raw materials were analyzed for correspondence with these requirements. The technology of obtaining WSPC and PS from fruits and herb of anise has been developed. For a new herbal medicine - pectins from the herb of anise ("Pectan"), standardization parameters were proposed and 5 batches were analyzed for correspondence with these requirements; developed the project QCM "Pimpinella anisum herb pectin substances". The conducted pharmacological researches established acute toxicity, antimicrobial activity and laxative effect of WSPC and PS isolated from the anise herb. The composition and technology of obtaining effervescent granules of PS from anise herb are substantiated, their standardization is carried out

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