Chaika N. The phytochemical study of bearberry leaves and creation of new medicines based on them

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0822U101036

Thesis Registration Form

0822U101036.pdf

Applicant for

Specialization

  • 226 - Фармація, промислова фармація

02-09-2022

Specialized Academic Board

ДФ 64.605.039

National University of Pharmacy

Essay

The thesis is devoted to the phytochemical study of bearberry (Arctostaphylos uva-ursi) leaves and dry extracts from this raw material to create new standardized medicines with diuretic, anti-inflammatory, hypoglycemic and hypolipidemic effects. The phytochemical screening of the main groups of biologicaly active substances (BAS) in bearberry leaves showed the presence of hydroquinone derivatives, phenol carboxylic and hydroxycinnamic acids, coumarins, flavanoids, tannins and triterpene saponins. At the same time, such substances as arbutin, gallic, ellagic, protocatechoic, chlorogenic and p-coumaric acids, quercetin, rutin, hyperoside, galo- and ellagotanins were identified by TLC. The quantitative content of the main groups of phenolic compounds in the raw material was determined.

Read more

Files

autoreferat-Анотація_Чайка Н.Б..docx

disertacija-chajka-n.b..pdf

Similar theses

0824U001151

Nataliia M. Sakhnatska

Scientific and methodological approaches to the implementation of the concept of holistic marketing in pharmacies in conditions of digitalization.

0824U001043

Viktoriia V. Zhurenko

Development of the methodology for the implementation of the environmental management system at domestic pharmaceutical enterprises. – Qualifying scientific work on manuscript rights

0824U001034

Yevhen O. Tantsura

Experimental study of the effectiveness of antiepileptic drugs in the treatment of seizures in mice with corneal kindling on the background of potential modulation of enzymes of the cytochrome P450 system

0824U001012

Anton P. Semenets

Molecular modeling and synthesis of biologically active substances with nootropic action in a series of 4-R-1-benzylpyrrolidin-2-one derivatives

0824U001013

Bohdan S. Leontiiev

Pharmacognostic study of Viburnum opulus fruits as a promising source of medicinal plant raw material