Borko Y. Development of composition and technology of rectal suppositories with diosmin and hesperidin

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0823U100177

Thesis Registration Form

0823U100177.pdf

Applicant for

Specialization

  • 226 - Фармація, промислова фармація

23-03-2023

Specialized Academic Board

ДФ 64.605.049

National University of Pharmacy

Essay

The dissertation is devoted to the theoretical and experimental substantiation of the development of the optimal composition, technology and quality control methods of rectal suppositories with diosmin and hesperidin for the treatment of diseases of the anorectal zone. For the first time, the combined use of diosmin, hesperidin and benzocaine in one medicinal form was proposed. The possibility of increasing the bioavailability of substances under the influence of difil suppository base has been proven. As a result of the analysis of the therapeutic possibilities of treatment of proctological diseases, the expediency of using herbal phleboprotectors (diosmin and hesperidin) as active pharmaceutical ingredients was revealed. The use of benzocaine as an additional therapeutic agent is substantiated

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Files

autoreferat-анотація.docx

disertacija-borko-ie.a..pdf

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