Burdenyuk I. Clinico-experimental substantiation of enterosgel application in a complex treatment of patients with acute purulent diseases of the uterine adnexae.

Detoxicative and microbosorptive properties of enterosgel in the experiment on a purulent peritoneal exudate in vitro (11 stages of research) and 56 on mongrel dogs were studied. A high sorptive ativity of enterosgel lasts for 3 days. The sorbent combination with gentamycinum sulfat intensifies a detoxicative effect. A complex clinical-laboratory examination of 78 women from 15 to 48 years of age, 58 of them afflicted with acute purulent - inflammatory diseases of the uterine adnexae (pyosalpinx, pyovar) was conducted. 41 patients (70,7%) had a disease without any complications and 17 patients (29,3%) had a purulent - inflammatory process complicated with peritonitis. All the patients were operated on and a purulent source was removed. In case of peritonitis lavage and drainage of the abdomen were applied. The peculiarities of clinical course of a post-operative period in patients with acute purulent diseases of the uterine adnexae and peritonitis on the basis of enterosgel application per os and intra peritoneally through the drains were examined. The results of clinical-laboratory examinations are indicative of a high activity of enterosgel with the decrease of symptoms of the blood endotoxicosis.