Chokina O. Comparative characteristic of erricacy of diagnostic method and medication of urogenital chlamidial infection

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U001000

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

15-03-2001

Specialized Academic Board

Д 41.600.01

Odessa National Medical University

Essay

113 urogenital chlamidiosis female patients and 11 healthy women have been examined. Diagnostic methods of chlamidios (cultural, complement fixation reaction-CFR, immunofluorescent analysis-IFA, direct immunofluorescence-DrF, chain polymerase reaction-CPR) have been considered to be the most valuable in diagnosis of chlamidiosis. A considerable member of falsepositive data (20%) has been received whire using CPR. The role of gypoestrogenia, decrease level of progesterone and immune disturbances in pathogenesis of urogenital chlamidiosis has been demonstrated. Complex medication of chlamidiosis has been carried on before pregnancy. The main group of women received inductor of endogenous interferon --amixin, along the specific medication. Control group of woman used traditional immunomodulatoes. Hogh efficacy of complex medication of chlamidiosis with amixin has been shown. Pregnancy should come at least in 6 months after medication of urogenital chlamidiosis proved to contribute to preparation of a wome n for pregnancy, labor, redice the risk of intrauterine infection of a fetus and morbidity of newborns

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