Zakharchuk O. Use of tinned biomaterials at surgical treatment of extensive postoperative ventral hernias in the infected wound.

The object of research: The postoperative and recurrent ventral hernias, which appeared in a consequence of purulent-inflammatory complications in the postoperative wound after conducted operations. The purpose of study: The complex experimental morphological and clinical study of grafting of tinned transplant "Tutoplast" in infected wound and preventive management of graft rejection.Methods of research: The complex clinical investigation was carried out by the patients with the purpose of learning of the common state. The standard clinical methods of definition of common analysises of blood and urine, biochemical analysis of blood sugar and urea, a level of a bilirubin and electrolytes of structure in blood were used. Chest X-ray, spirography, ECG fulfilled by the patient for a definition of the functional state of respiratory and cardiovascular systems. The study of the local status carried out with the help of the clinical procedures, of the data herniometry and results of ultrasonic research abdominal cavity in a region of the hernial hiluses. The immunological status was researched by the standard procedures with definition of the parameters cell's and humoral's immunity.Practical significance: Simple and reliable technique of protection from tinned transplant rejection in infected wound is developed. The proposed technique is proved by results of conducted researches, by local application of new combined preparations on hydrophilic base with antibacterial and absorptive properties. Healing process of activated significantly.Scientific novelty: For the first time on the experiment of researches the features of implantation and modification of a tinned transplant in infected wound are determined. It is proved that the local application of combined preparation antibacterial and stimulating reparations of a wound provides optimal improvement of healing process limiting tissue inflammatory response while healing of a wound with primary tension. Introduction: The developed method was inserted in the work of surgical departments of the urban clinical hospital №2, municipal hospital №18, municipal hospital №26 in the Kharkov, municipal hospital №5 in the Sumy. The main positions of the thesis are using at reading of the lectures to the doctors KMAPE. Sphere of application: medicine, surgery.