The object of investigation - state of resistence in piglets at the age of 5-7 days till 130 days of their life, which are growing at farms where they are kept. The purpose of investigation - theoretical grounding, studying of action and optimization of using the technology of natural immunomodulated CAFI preparation for increasing the resistance and productivity of piglets during their growing in conditions of pig-breeding farms. Methods of investigation and equipments. Physiological, hematological, immunological, biochemical, zootechnical, zoohygienic, veterinary and sanitary, statistic. Photoelectric colour-measuring equipment, centrifuge, microscop, biochemical analyzer "Super-Z". Scientific novelty of received results consists in complex experiments of physiolo-immunological indices, which characterize the Cell and Humoral factors of piglets resistance using immunomodulated preparation thymus(CAFI). Owing to conduct experiments, it was proved that CAFI preparation which was given to piglets normalize the cell factors of resistance of organism: increase the proliferation, accelerate the maturity and specialization of lymphatic cells and cells of mielocytaric series, which promotes the increase of their functional activity. The regime of using the CAFI preparation for young pigs was worked out, and it was determined their optimal variant which favour the increase of resistance and productivity of piglets. Subject and the degree of introduction. Which the purpose of normalisation the fraction of resistance, increasing the metabolism and productivity of piglets, which are growing at modern farms of state and private property, it was proposed to use it according to regime three times: the first injection - at 5-7 days of birth, doze - 0,05 ml/kg of animals living mass; the second - in 14 days, doze - 0,02 ml/kg, the third - in 7-10 days before getting from, doze - 0,02 ml/kg. The efficiency of introduction: the results of investigation are included into recommendations due to the correction of resistance cell indices in organism of young pigs and CAFI preparation using at veterinary serving of animals which are confirmed at scientific Technical Board of the Department of Veterinary Medicine at Ministry of Agrarian Politic of Ukraine. Results of the work are introduced in agricultural production stuff "Ustymivskyj", Vasylkivskyj district, Kyjiv region. Sphere (field) of using: in pigs-breeding; in educational process at teaching physiology of farm animals for students of agrarian higher schools, Ш-IY levels of accreditation.
