Kokovska O. The blood coagulation peculiarities in the symmetrical regions of blood circulation system in peoples and animals

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U004876

Applicant for

Specialization

  • 14.03.03 - Нормальна фізіологія

27-10-2004

Specialized Academic Board

Д 11.600.01

Essay

Subject- the peculiarities of a blood coagulation process in the symmetrical regions of the circulatory system in healthy humans and animals. Purpose - to detect the presence or absence of asymmetry in the symmetrical regions of the circulatory system in healthy humans and animals under physiologic conditions as well as in cerebral circulation disturbances in experiment. Methods - coalologic, biochemical, statistic. Results - symmetry in the symmetrical regions of the circulatory system has been found. Uniform approaches to blood analysis making are to be selected. Novelty - on the basis of received data assigne the "rught" and "left" haemostasis asymmetries type. It was shown in the work that asymmetries depends on the tissue haemocoagulative factors activity in the appropriate blood circulation region. It was proved for the first time that the symmetrical blood circulation regions asymmetries, particularly the brain one, depends on the peroxidative lipid oxidation reactions and antioxidative enzymesactivity in the brain hemispheres. It was established that in the experiments models at the acute and chronic brain circulation disturbance in animals haemostasis asymmetries depends of activity peroxidative lipid oxidation reactions and antioxidative enzymes activity. It was been introduced in the academic process of medical higher schools. Field - medicine.

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