Rebkovets I. Thyroid system dysfunction at the severe craniocerebral trauma, the methods of their correction

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U000969

Applicant for

Specialization

  • 14.01.30 - Анестезіологія та інтенсивна терапія

15-10-2004

Specialized Academic Board

Д 08.601.01

Essay

All patients with severe craniocerebral trauma (SCCT) were randomized into three groups. The patients of the 1-st group got the standard intensive care. To the intensive care complex of the patients of the 2-d group morphine was added in small doses. Except the standard intensive care the patients of the 3-d group got the replacement therapy with thyroid hormones. The patients of the 1-st group had the "low T3 syndrome". The level of triiodthyronin (T3) is the prognosis criterion of the issue of SCCT during the taking of the standard intensive care complex. During the administration of morphine in small doses the "low T3 syndrome" wasn't formed in the patients of the 2-d group as a result of activating the central section of hypothalamus-hypophysis-thyroid system (HHTS). During the administration of morphine in small doses the level of thyrotrope hormone (TTH) is the prognosis criterion of the issue of SCCT. During the taking the replacement therapy with thyroid hormones the patients of the 3-d groupdidn't have the "low T3 syndrome" as a result of influencing the peripheries section of the HHTS. During the exogenous introduction of thyroid hormones the prognosis criterion of the issue of SCCT is the level of thyroxin (T4).

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