Piddubna O. Characteristics of EEG and responsiveness of the cardiovascular system as indices of the adaptive abilities of the organism in children.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U001932

Applicant for

Specialization

  • 03.00.13 - Фізіологія людини і тварин

11-04-2006

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

Systemic approach was applied in the diagnostics of disorders of adaptation in children using quantitative analysis of electrical activity of the brain and reactions of the cardiovascular system. Data of cardiointervalography (CIG) and rheoencephalography (REG) obtained for 37 healthy children and 63 children suffering from bronchial asthma (BA) allowed us to identify most informative indices characterizing reactions of the cardiovascular system under conditions of an active orthostatic test (index of autonomic reactivity and index of vascular reactivity). Considering relations between these indices, it was possible to classify the following gradations of the state of adaptation systems of the organism responsible for the quality of the control of the autonomic sphere. In about 30 % of healthy children, a deficiency of the adaptation abilities was found (a group of risk), while the frequency of adaptation disorders was significantly higher in the group of patients with BA. Results of normological examination of 169 healthy schoolchildren (6 to 17 years) using computer periodometric analyses allowed us to obtain quantitative parameters characterizing the temporal structure of EEG in these children and to propose a classification of the EEG-patterns. It is shown that groups of healthy children and patients with BA differ from each other in proportions of different patterns of current EEG and variants of hyperventilation-induced EEG reactions. Qualitative and quantitative characteristics of EEG in children, despite high individual variability, clearly correlated with the state of adaptation processes.

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