Myronenko V. Optimization of diagnosis of digestive organs' affections at chronic opisthorchiasis

The clinical, clinical laboratory, immunological and instrumental methods were studied and evaluated comparatively at examination of the patients with chronic opisthorchiasis at different stages of the disease. The previously unknown relation of the values of the indices of the studied methods and the invasion process duration has been revealed. The evaluation of the studied methods from the point of view of their diagnostic value demonstrated that some of them (hepatoscintigraphy, echosonography and contact liquid cristallic thermography) which are characterized by high informativity (73-93 per cent) about the character and activity of the process in the organs of hepatogastroduodenopancreatic zone may be used as additional criteria while establishing diagnosis. The most prognostically informative methods are reohepatographic and immunological criteria compared to the clinical and clinical laboratory ones. The complex study of the changes in the proportion of the values of the immunity indices and disorders of hepatogastroduodenopancreatic zone organs allows to evaluate objectively the condition of the organism of the patients with opisthorchiasis, to provide a differential antihelmint and pathogenic therapy as well as to predict the efficiency of the treatment of opisthorchiasis and its complications/