Perchyk O. The preservation of the extract of placenta on the stages of low temperature keeping and its effectiveness in urogenital violations and climacteric disorders of women.

The performed researches have allowed to determine. that the optimum condition for low-temperature keeping of the cryoextract of placenta. that does not lead to the essential deprivation of hormonal component, is the keeping at the temperature of 20 o C within 10 days with its following keeping at the temperature of the liquid nitrogen -196 o C up to 1 year. Besides it has been experimentally established, that a revitalising action which results in improving of the morphofunctional condition of the parenchymal organs takes place in the course of injection of the cryoextract of placenta as well as replanting of a placenta fragment for old animals. It was proposed to introduce a new treatment mode of urogenital violations and climacteric disordes of women with the preparation "Cryocel-cryoextract of placenta". This mode consists in the intramuscular injection of 1,5 ml of "CEPI" with the periodicity one time in three days - 5 injections during the course of treatment with vaginal tampons impregnated withthe preparation being inserted at the same time. The comparative analysis of the therapeutic action of the preparation "Cryocell-cryoextract of placenta" and "Ovestin", used in the clinical practice in overwhelming majority of cases has been conducted in the present thesis. The evident effectiveness of the preparation "Cryocell-cryoextract of placenta" using was ascertaind and it was proved out with clinical-and-laboratory methods.