Konovart O. Mechanism of effect of blockers of H2-hystamine and M1-cholinergic receptors in peripheric blood limphocytes

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U002224

Thesis Registration Form

0408U002224.pdf

Applicant for

Specialization

  • 14.03.03 - Нормальна фізіологія

16-05-2008

Specialized Academic Board

Д 35.600.03

Essay

Dissertation is devoted to studying of human peripheral blood on permeabilized mononuclear lymphocytes glutathione antioxidant system role and transporting ATPase in realization of Н2-histamine receptor blocker effects, М1-cholinergic receptors and proton pump blocker. Lymphocytes are shown to be an adequate model for exploring of enzyme functioning mechanisms of glutathione antioxidant system and transporting ATPase. Н2-histamine receptor blockers, М1-cholinergic receptors, proton pump respectively were proved to have another mechanism of action besides basic one. Аs lipid peroxidation, glutathione antioxidant system enzymes and ion-transporting systems are involved in it.

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Files

автореферат.doc

дисертація.doc

дисертація.doc

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