Kondakov I. Anti-atherogenic effect of cryopreserved placenta at experimental atherosclerosis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U002316

Thesis Registration Form

0408U002316.pdf

Applicant for

Specialization

  • 14.01.35 - Кріомедицина

22-04-2008

Specialized Academic Board

Д 64.242.01

Institute of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine

Essay

The thesis covers studying anti-atherogenic effects of cryopreserved placenta at experimental atherosclerosis. It has been shown that introduction of allogenic cryopreserved placenta to the rabbits with experimental atherosclerosis during the first week resulted in the normalization of lipid exchange, statistically significant rise in the level of estradiol in blood serum. To the 3rd week after introduction of anti-atherogenic cryopreserved placenta (ACP) the number of "lipid-loaded" leukocytes in peripheral blood approached to the control values, statistically and significantly reduced the area of aorta damage with no stage of atherocalcinosis. In 6 weeks it caused neovascularization of myocardium and recovered structural and functional integrity of aorta vascular endothelium

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Files

aref.doc

diss.DOC

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