Litvinova L. Effect of cryopreserved fetal neural cells on reparative process in pathologically changed retina.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U002391

Thesis Registration Form

0408U002391.pdf

Applicant for

Specialization

  • 14.01.35 - Кріомедицина

20-05-2008

Specialized Academic Board

Д 64.242.01

Institute of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine

Essay

The thesis covers studying the effect of cryopreserved fetal neural cells after being introduced during treatment of dystrophic pathology of vision organ. The possibility of participation of cryopreserved fetal neural cells in recovery of anatomic retina structures has been shown. Reparative regeneration in the damaged retinal membrane at molecular level of regulation of the processes: based on studying the production of some neurotrophic factors (TGF -1 and GNF) directly participating in reparative regeneration has been investigated. It has been shown that the introduced neural cells are highly pathological focus-seeking and found in the damage focus within a long period up to 21 days. As the matter of the record on obtained experimental data a high efficiency in ophthalmologic practice during treatment of dry form of central chorioretinal dystrophy has been demonstrated. This method may be introduced into daily ophthalmologic practice and contribute to social rehabilitation of the patients. Key words: cryopreservation, fetal nerve cells, reparation, retina, application

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Files

Автореферат Литвиновой Л.В..doc

Диссертация Литвиновой Л.В..doc

Диссертация Литвиновой Л.В..doc

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