Vaselenko V. Status of the uterine cervix in pregnant women at risk of cervical incompetence and miscarriage.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U005614

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

16-12-2008

Specialized Academic Board

Д 26.553.01

SI «Institute of Pediatrics, Obstetrics and Gynecology named academician O. M. Lukyanovaya NAMS of Ukraine»

Essay

30 women with uncompromised anamnesis and 171 women from the cervical incompetence and miscarriage risk group were fully examined in course of pregnancy. The sequence of deterioration of the uterine cervix ultrasound parameters in course of forming of the cervical incompetence depending on the gestation terms and the anamnesis data was described for the first time. It was established that with increase of the degree of the risk the number of the cases with the changed internal os also increased as well as the manifestations of the latent cervical incompetence. It was shown that the less compromised the anamnesis was, the later the changes of the internal os appeared, and the more functional nature they had. It was proved for the first time that the terms of manifestation of the cervical incompetence typical for the lower risk groups remained for the higher risk groups as well. On the basis of the mathematical analysis there was suggested a concept of cervical competence continuum which lead to formingof the cervical incompetence and for the first time took into account presence of two biological components of the cervix "locking mechanism". The suggested concept provides for the fact that a pregnant uterine cervix was in one of the following functional states: a) physiological state; b) isthmic incompetence; c) functional (relative) cervical incompetence; d) absolute (organic) cervical incompetence. Performing of the complex ultrasound examination of the uterine cervix allowed getting 2,5 times decrease in miscarriage rate comparing to the history data (up to 17,4 %).

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