Object of research: pharmacological-toxicological description new insectoacaricides preparation "Ektosan" in medical forms solution and powder. Purpose of research: to make recipe new insectoacaricides preparation in medical forms solution and powder, to broad spectrum ectocides action in constant and temporary ectoparasites mammal and bird, and parasitological fly insects. Determination pharmacological-toxicological valuation preparation "Ektosan" in forms solution and powder, to have scientific substantiation of it use in modern poultry industry. Methods of research: pharmacological, toxicological, biochemical, epizootological, clinical, parasitological, electro-microscopically, statistical. Scientific novelty: we were the first to compose in Ukraine preparation "Ektosan" and carry out pharmacological-toxicological valuation in medical forms solution and powder, carry out parameter acute and chronically toxicity. Experimentally research demonstration that insectoacaricides preparation "Ektosan" in medical forms solution and powder has insectoacaricides action in ectoparasites mammal and bird: acaroids - parasitiformes tick (family Ixodidae, Argasidae, Dermanyssidae), acariformes tick (family Sarcoptidae, Psoroptidae, Cheyletidae), trombidiformes tick (family Dermodecidae); entomosis -representatives of class of Insecta and in also time shows a stable repellent effect ("Ektosan-pudratm",). It is set specific picture of ectoparasitoses of birds in the poultry farms different kind of property in central and northeastern regions of Ukraine, and also possibility of to give is well-proven domestic that synanthropic bird at their contact. It is recommended to application in the poultry farming economies of different production direction complex of medical-profilaction measures from warning of origin of ectoparasitoses of birds. The scientific novelty of this mean is confirmed by a pa-tent on an useful model: u 200806691, Ukraine, А61К31/01, А61Р33/00. Insectoacaricides preparation of "Ektosan ". Degree of introduction: suggestions to practice - methodo-logical advices "Exciters of basic ectoparasitess of poultry are expounded in methodical recommendations and aspects of application of new facilities and control methods them on objects poultry farming", which are ratified by scientific and technical counsel of statutory broker of veterinary medicine, protocol № 1, from 24.12.2008 and recommended to the use by the veterinarians of poultry farming economies, listeners of the inplant and students of higher educational establishments training for specialities a 7.130501 "Veterinary medicine". Serial production of the "Ektosantm" and "Ektosan-pudratm" product on the scientific-productive company "Brovafarma" is implemented. Sphere (field of using): veterinary medicine.