Kulik A. Clinicopsychological peculiarities in patients with ischemic heart disease

Dissertation is devoted to development of the medicopsychological accompaniment system of patients with ischemic heart disease on the basis of clinicopsychological indexes dynamics study. 142 patients (77 men and 65 women) with the pain form of IHD in age from 45 to 60 years were examined. On the basis of clinicopsychological indexes determination (general QoL index (GQoLI), levels of depression, anxiety, patient's state of health estimation and pain perception; type of relation to the illness, functional class (FC) of exertional angina (EA) and HRV - indexes of total power (TP) of HRV spectrum, powers of subdomains of very low (VLF), low (LF), high frequencies (HF) and LF/HF ratio) in patients with IHD in groups with a presence and absence of the depressive disorders at the beginning, in 3 weeks, 3, 6 and 12 months of basic therapy, it was determined, that the depressive disorders result in worsening of QoL and HRV indexes. It was shown, that basic IHD therapy in the group of depressed patients with positive dynamics doesn't allow to attain QoL and HRV indexes, registered in the group of non-depressed patients. It was determined, that using of cognitive psychotherapy and adding of tianeptine to basic IHD therapy in depressed patients allows not only to improve QoL and HRV indexes, but also attain the values of the proper indexes as in non-depressed group. Key words: ischemic heart disease, depressive disorders, quality of life, heart rate variability, tianeptine.