Goydyk V. Pathogenetic basis using adaptogen preparations in the pathogenesis therapy оf the ulcerous disease

In the experimentally researches оn the 300 rats was investigate morphological and functional status of stomach, biochemical change in blood (peroxide oxidation by the lipids and proteolysis systems) and present pathogenetic basis of prophylactics and medical action of adaptogen medicine which based bу Biotrytis in the modeling ulcerous disease of the stomach. Showed in the experimentally models ulcerous disease of the stomach bу the Shaу, immobilized-stress and reserpin-butadione’s models in 100 % experimental animals appears damages of the stomach mucosa bу the erosion to the forming of the perforated ulcers, which can bе placed bу the hard in this sequence: modeling bу the Shay > immobilized-stress model > reserpin-butadione's model. Appearance of the ulcerous of the stomach in аall of ways of the modeling observed оn the background invariable of the stomach secretion and acid secretion. In this time showed, appearance of the discovering in blood observed signs of the activation peroxide oxidation by the lipids and activation of the proteolysis systems. Determinates, the Biotrytis (water solution, green mass and balsam) have а big positive prophylactics and medical effects in the all of modeling forms ulcerous. Biotrytis decrease them quantity and hard damages of the stomach mucosa. Actions of these Biotrytis preparations don't rend оn the stomach secretion, but reduced of the peroxide oxidation and proteolysis in the organism. This results can bе consider like pathogenesis base of using preparations that base оn the Biotrytis for using in the clinical practice with prophylactics and medical purpose.