Basatskiy A. Prognostication of results and increase of efficiency of operations on the deep femoral artery at the chronic ischemia of lower extremity

Object - a chronic ischemia of lower extremities; the purpose - To improve results of surgical treatment of patients with multiple stenotic lesions tibial arteries by improving methods revascularization operations on lower extremity bone system based on clarifying the mechanisms of therapeutic actions and indications for the use of optimization in chronic ischemia; methods - clinical, triplex ultrasound scanning, Doppler ultrasound, angiography, measure transcutaneously oxygen tension, X-ray study of the leg bone, the analysis of cell proliferation (MTT-Cell Proliferation Assay), statistical; novelty - The first sound anatomic-hemodynamic criteria for use revascularization forecasting operations at the bone system in patients with chronic ischemia of lower extremities. For the first time proved the effectiveness circuitous revascularization methods in patients with trophic disorders in chronic ischemia of lower extremities. The first set availability stromal stem cells in bone marrow areas bone perforation and found them reduced functional activity. For the first time on the basis of clinical and instrumental studies revealed similarities in the application process revascularization forecasting operations at the bone system and autologous stem cell transplantation; results - Using the proposed method of treatment has allowed us, you have achieved clinical improvement in 95.1% of patients studied group; is introduced - into medical practice, in educational process; area - medicine.