Yudin O. The proofing of applying of miniinvasive interventions in surgical treatment of patients with acute pancreatitis

Subject of inquiry: Acute pancreatitis; The aim of the research: improvement of surgical treatment results of patients with acute pancreatitis by means of development of diagnostic techniques and principles of minimal invasive interventions usage; Methods: clinical, biochemical, immunochemical, pathologic, radiologic, ultrasonic investigation, biostatistics methods; Scientific novelty: The surgical approach of patients' management with acute pancreatitis was developed that was based on the pathologic development phases of the disease with use of minimal invasive interventions under guidance of ultrasound. The optimal approach to performing different kinds of minimal invasive interventions was developed depending on topographical anatomical location of destruction foci in acute necrotizing pancreatitis and its complications. Sonographic signs of acute pancreatitis and its complications were improved and systematized and ultrasonic investigation algorithm of hepatobiliary zone was created; Results: It was proved that ultrasonic investigation was the main method of acute pancreatitis diagnostics. Use of ultrasonic investigation algorithm and sonographic monitoring in diagnostics and treatment of acute pancreatitis gave the possibility to determine epigenetics of the pathologic process that was considered to be the main factor in choice of surgical approach. Application of minimal invasive intervention under guidance of ultrasound in surgical treatment of patients with acute pancreatitis made it possible to improve treatment results and reduce postsurgical lethality from 36.3% to 3.2%; it is inculcated - in medical practice, in an educational process; sphere - medical practice.