Huz Y. Kormosantm is pharmacodynamics and use at mikotoksicozis of pigs

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U001104

Applicant for

Specialization

  • 16.00.04 - Ветеринарна фармакологія та токсикологія

16-12-2010

Specialized Academic Board

Д 35.826.03

Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv

Essay

Object of researches: a pharmacodynamics and application of adsorbent of "Kormosan" are at mycotoxins of pigs. Purpose of research: the aim of researches was: ground of compounding of new adsorbent of "Kormosan" for warning of mycotoxins of animals; research of him pharmako-toxicological indexes; development of charts of application of this mean is at presence of forage for pigs, that with a different degree of mycotoxins. Methods of researches: clinical, pharmacological, toxicological, haematological, biochemical, epizootilogy, electronic-microscopic, statistical. Scientific novelty: research of contamination of forage is first conducted mycotoxinsat the specialized pig breeding economies of the North-eastern region of Ukraine. Mycotoxins which was in feed forage in the economies of this area and description toxicness of distinguished mycotoxins is found out. The most optimal method of exposure of mycotoxins is certain in the mixed fodders, which it is enough to the fasts (research duration presents about 30 min). The new home mean of "Kormosan" is first worked out for the detoxication of mycotoxins. He is conducted pharmako-toxicological estimation with determination of parameters of sharp and chronic toxicness, and also methodologies are offered for determination of content of selenium and content of salts of heavy metals in composition of compounding by the new method of spectrophotometry. It is experimentally well-proven that "Kormosan" provides a prophylactic and medical action at mycotoxins of pigs. Degree of introduction: THAT is worked out In, instructions and other normatively-technical documentation, had state registration of new adsorbent with the patent name "Kormosan" and a registration certification is got and patent for Ukraine on an useful model №49087 is Feed addition for adsorption of mycotoxins of "Kormosan". The worked out recommendations "Mycotoxins of pigs and bird : bases of diagnostics facilities and methods of medical and preventive correction", which are approved by scientific and technical advice of the State committee of veterinary medicine of Ukraine (protocol №1 from 24.12.2008) it is offered to the use of veterinary medicine of pig breeding and poultry farming economies, listeners of in-plant training and students of higher educational establishments specialists on speciality 7.130501 "Veterinary medicine. Sphere (field of using): veterinary medicine.

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