Polinchuck I. Character and rate of restoration of the psychophysiological duties after various kinds of general anaesthesia in the conditions of one-day hospital and optimization its restoration

The dissertation is devoted to the problem of safety of the general anaesthesia in one-day hospital. The restoration of cognitive functions provides safety of patients in early and quality of their life in the remote period after operation. Research of 136 patients has shown, that the main reason of breaks cognitive functions after operation is negative influence of preparations for the general anaesthesia on the central nervous system. Restoration cognitive functions fastly occurs at application propofol (7-30 day), more slowly at application thiopental sodium (30 day) and ketamine (30-90 day and more). The first restore simple cognitive functions, then more complex. Application pharmacological neuroprotection thiocetam has authentically sped up restoration cognitive functions at all researched methods of anaesthesia. At use propofol an initial level cognitive functions it has been achieved in the early period after operation, at use thiopental sodium and ketamine - in 7 day. The method of an integrated estimation of a condition of patients at the moment of an extract from one-day hospital after the general anaesthesia on clinical, laboratory, cognitive to parameters is offered.