Puchkov V. State of feto-placentary complex and system of immunity for pregnant with the premature rupture of amniotic membranes in the terms of gestation 22-28 weeks

The dissertation is devoted to the problems of rational management of pregnancy and delivery of women with premature ruptured membranes in the terms of gestation 22-28 weeks. Based on a comprehensive study of the basic certain risk of premature rupture of amniotic membranes and infectious complications factors in pregnant, obstetric complications and perinatal consequences. First on the basis of complex research of 122 pregnant women in the terms of gestation 22-28 weeks defined that presence of E. coli of pregnant women with incomplete pregnancy complicated by premature rupture of amniotic membranes with long term waterless, influences on development of horioamnionitis. Based on a comprehensive study of immunological research show early diagnostic markers of development of infectious complications.Ascertain that premature rupture of membranes of pregnant in the terms of gestacion 22-28 weeks and the protracted waterless interval (more 48 hours), does not influence on the state circulation of the blood placenta-fetus, including signs of infectious complications of such pregnant.The got results became theoretical pre-condition for development of the new point of view to observe fpregnant women with the premature rupture of membranes and protracted waterless interval in terms 22-28 weeks gestacion.It is well-proven that duration of waterless interval for these pregnant does not have a qualificatory influence on frequency of origin of infectious complications at a mother, antenatal fetus and newborn. A risk in case of horioamnionitis factor is a presence of premature ruptured membranes, but not duration of waterless interval. At development of premature rupture of membranes in terms 22-28 weeks and by the protracted waterless interval, prolongation of pregnancy reduces a mortinatality almost in 4 times