Pulyaeva I. Diagnostic and treatment of deep vein thrombosis of lower extremities in cancer patients taking into account the prognostic assessment of their development

Research results of 156 patients with deep vein thrombosis of lower extremities and (or) cancer patients were presented in the work. The study identified a number of new hemostatic, diagnostic criteria, identified prognostic assessment of deep vein thrombosis in cancer patients, thus improving the accuracy of diagnosis of venous thrombosis, the validity and effectiveness of surgical intervention. In this paper the possibility of surgical treatment of cancer pathology in acute venous thrombosis without increasing the risk of venous thromboembolism. The methods appropriate surgical interventions for deep vein thrombosis of lower extremities, depending on the condition of blood clots and the need for urgent treatment of tumors. Introduced the method of selective embolization of distal tumors. An algorithm for prevention of venous thromboembolism in cancer patients with taking into account the prognostic assessment of their development, based on changes in parameters of blood coagulation. Improved tactics of anticoagulant therapy in cancer patients. Proved highly effective surgical treatment of deep venous thrombosis of lower extremities in the acute phase is based on an analysis of the immediate results of treatment of cancer patients with DVT. Assessed the need for cancer screening in patients with unprovoked venous thrombosis of lower extremities Revealed unidirectional changes in the walls of the thrombosed veins of cancer patients and patients with deep venous thrombosis: a significant decrease in the thickness of the vessel wall, as well as its basic structural components. At the same time, it is proved that the development of venous thrombosis in cancer patients is directly stimulated by the tumor process.