Novoskol'tseva I. Prophylaсtic measure and surgical treatment of the sharp gastro-duodenal bleeding in patients with chronic renal failure

Research results of 116 patients with CHRF were presented in the work. In the basic group were patients with the gastro-duodenal bleeding, in the group of comparison were patients with CHRF without the signs of bleeding. The pathological changes of gastro-duodenal mucous membrane were revealed in 33,4% of patients. Painless form of defeat of gastro-duodenal area were revealed in 45,8% of patients. The patients had a primary defeat of antral department of stomach and bulb of duodenum. Erosive - ulcerous defeats often were found in patients which were received gemodializ. The main course of bleeding in the patients of basic group were sharp ulcers (87,0%).Helicobacter pylori was exposed in 31 patient (57,4%) in the group of comparison, in 55 patients (88,7%) of basic group. In patients with the gastro-duodenal bleeding the giperacidnoe state was exposed at 56,4%, in the group of comparison was exposed 44,4% of patients. The indexes of mikrocirculation brought down from the body of stomach to the bulb of duodenum. The most gross violations of mikrocirculation were presented in patients with the gastro-duodenal bleeding.Operative interference was accomplished in 18 (29,0%) patients of basic group. Endoskopic injection gemostaz with the use of facilities which make better mikrocircula-tion (argeninum gydrochloridi) conducted at 27 patients, electro-coagulation at 25. The large number of relapses of bleeding whith using of electro-coagulation was marked in 24% of patients. Developed complex of medical measures at the gastro-duodenal bleeding for patients with CHRF, with the helping of injection endoskopic gemostaza, allowed to shorten the risk of relapse of bleeding, reduce the terms of final epitalisaion of gastro-duodenal ulcers in 1,4 time.