Savytska M. The features of the esophageal epithelial mucosal barrier functional reorganization under the stress-induced injury: mechanisms and ways of correction

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0412U006860

Applicant for

Specialization

  • 14.03.03 - Нормальна фізіологія

14-12-2012

Specialized Academic Board

Д 35.600.03

Essay

The healing of nonerosive stress-associated esophagitis was estimated in time period after stress, we examined changes of serum content of VEGF, EGF, IL-1? and TNF-? and expression of glycoconjugates.. It was shown the structural and functional reorganization for subepithelial and epithelial structures under spontaneous repair and corrections with of melatonin and modification microbiota. It was established character of changes in subepithelial structures marked by lectins,and in level of VEGF і TNF-? can be potent diagnostic biomarkers for therapeutic approach of nonerosive esophagitis/

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