Glebov O. Especially of emotional response of rats with functional changes of cerebral circulation

Object - the cerebral circulation, the energy balance of the brain, behav-ior and emotional state of rats after an episode of functional change in cere-bral blood flow. Purpose - to identify features of the emotional state of rats after an episode of functional change in cerebral blood flow and to develop a mathematical model of evaluation of functional change in cerebral blood flow, taking into account behavioral responses of animals in the test "open field" and state of cerebral circulation. Methods - physiological, biochemical, physiological, statistical. Results - during modeling functional changes of cerebral circulation by combining head-down tilt under the angle of 450 with rocking during 1 hour statistically significant (p <0,05) changes appear in rheoencephalogram data that reflect the circulation in different parts of the vascular system of brain, as well as indicators reflecting cerebral energy ho-meostasis. Changes of REG disappeared 3 hours later after experimental ex-posure, and the restoration of energy homeostasis lasted for 1 day. The main factors were identified by using factor analysis of behavioral patterns and it was made physiological interpretation for them. Novelty - the most informa-tive indicators of REG and behavioral patterns for evaluating and predicting functional changes of cerebral circulation were identified through neural net-work modeling. The results of research have been introduced into education process of physiology departments of higher medical education establishments and into practical activity of scientific laboratory. Branch - medicine (normal physiology).