Muravskaya O. Clinical and instrumental characteristics of cardiogenic ischemic stroke caused by acute myocardial infarction.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U003952

Applicant for

Specialization

  • 14.01.15 - Нервові хвороби

26-06-2013

Specialized Academic Board

26.613.01

Essay

The dissertation focuses on improving the efficiency of diagnosis of cardiogenic ischemic stroke (IS), caused by acute myocardial infarction (MI) by studying features of neurological manifestations, cerebral and central hemodynamics, structural changes of brain, features MI, cardiac disorders. Stroke with MI had greater neurological deficit and worse functional recovery than those without MI. In the acute phase of MI evolved light cognitive impairment (CI), in the postinfarction period - moderate CI. Dominated medium and large foci of ischemia. At the haemodynamic stroke (HDS) foci were localized superficial in cortical - subcortical parts at the turn of vascular pools, they were irregular in shape. At the cardioembolic stroke (CES) - in cortical-subcortical regions of the left frontal lobe, had wedge shape. Occlusion of the artery on the side of cerebral infarction was caused by cardiogenic embolism with MI. Stenosis <50% on the side of ischemic lesion were not the direct cause IS, at the same time they worsen blood flow in MI. Much more often diagnosed MI with the wave Q, than MI without wave Q. Anterior MI occurred significantly more often than posterior MI. In the HDS often diagnosed common front and septal anterior MI, sinoauricular (SA-) and atrioventricular (AV-) block ІІ, violation of local contractility left ventricle (LV), reduction stroke volume (SV), LV ejection fraction, increase end-diastolic dimension, end-systolic dimension, end-diastolic volume and end-systolic volume. At CES significantly higher identified anterior-apical and septal MI, paroxysmal atrial fibrillation (AF), thrombosis LV, dilatation and thrombosis left atrium (LA), aneurism ventricular septal (VS). Consideration of the most informative parameters allows stages to achieve sufficient accuracy of diagnosis of stroke subtypes.

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