Burlachenko V. Condition and damage mechanisms of blood-brain barrier in HIV-infected patients

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U004940

Thesis Registration Form

0413U004940.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

05-07-2013

Specialized Academic Board

Д 29.600.02

Essay

Dissertation is devoted to the identification of the basic mechanisms of damage the blood-brain barrier (BBB) in the dynamics of HIV infection and the mechanisms involved in the damage of neuroglia complex hemispheres of the brain. Based on the study of material from the 245 peoples who died with AIDS/HIV, who were in the regional center to combat and prevent AIDS, revealed significant changes in the function of the brain and blood vessels ICR BBB, which were expressed in the increase in the content of endothelin-1 and reducing the activity of NO-synthase (NOx) in the endothelium. The changes revealed spasms of blood vessels and contribute to the development of hypoxia.

Read more

Files

aref.doc

diss.doc

diss.doc

Similar theses

0524U000146

Hennadii F. Stepanov

Pathophysiological mechanisms of ionizing irradiation influence on muscle tissue metabolism

0524U000051

Vitalii Kyryk

Pathogenetic mechanisms of realizing the regenerative potential of somatic stem cells, taking into account the criteria of their quality and efficiency

0523U100270

Olha H. Kmet

Pathogenic substantiation of the effectiveness of modulators of GABA-ergic and renin-angiotensin systems in experimental neurodegeneration

0523U100201

Iryna I. Kamyshna

Molecular mechanisms in the development of psychoneurological complications in patients with thyroid diseases: predicting onset and search for pathogenetic therapy

0423U100032

Havalko Anna Vasilivna

The role of hypoxia in impaired glucose tolerance in the elderly and ways of correction