Danylova Y. Prediction and prevention of perinatal complications in women with gestational hypertensive disorders.

Thesis's dedicated forecasting and prevention the perinatal complication women with hypertensive pregnancy disorders. Analysis of puerperal period in 445 puerperal made it possible to establish, that the hypertensive pregnancy disorders significant increase as AR so and RR miscarriage on 5,6 (RR - 2,48), caesarian - on 8,3 (RR - 1,76), fetal distress in delivery - on 7,8 (RR - 3,76), bleeding after delivery - on 11,0 (RR - 12,6), puerperal septic complications - on 6,2 (RR - 4,28). Research proved the autonomic nervous system by spectral analysis of heat rate variability due to constant increase of sympathetic nerve system (p<0,05) and decrease of parasympathetic nerve system (p<0,05) then in patients of hypertensive pregnancy disorders. Increase of sympathetic nerve system on the background of oppression parasympathetic activity on the first period of delivery (р<0,05). Three months after delivery found lag recovery of indicators autonomic nervous system by normal physiological level (p<0,05). It was proved during the research that "partner delivery" program presence results in normalization in autonomic regulation during of gestational and first period of delivery (p<0,05). Three months after delivery autonomic nerve regulation returner to the level physiological level healthy patients (p<0,05). By the method of neural network modeling and according to the results of observation the models of complications' prediction in women with hypertensive pregnancy disorders have been constructed. Combinations of factors which define the greatest risk degree of occurrence of these gestational and perinatal complications have been revealed. It has been proved that participation of a pregnant woman in the "Family delivery" program had significant influence on the decreasing of risk for gestational and perinatal complication.