Rudyk H. Toxic morphological grounds of disintoxicant application at presence of T-2 toxicosis

The subject: toxic-morphological assessment of sodium hypochlorite solution of high purity and feed additive "Aliosept". Objective research: tests of disintoxicational influence of sodium hypochlorite solution of high purity and feed additive "Aliosept" based on studying of the dynamics of pharmacological, toxicological, hematological, biochemical, immunological indices and histological, structural changes in rat, hen and pig liver under T-2 toxicosis. Test methods: pharmacological, toxicological, clinical anatomical, morphological, biochemical and immunological, statistical. Scientific innovation: disintoxicational liver function and the dynamics of structural changes of liver and kidneys of white rats, hens and piglets under T-2 toxicosis and after the application of sodium hypochlorite solution of high purity and aliosept were widely studied and scientifically grounded. The scientific information about neutralization mechanisms of T-2 toxin was significantly expanded, some indices of natural resistance were determined (level of bactericidal and lysozyme activity of blood serum) in rats, poultry and piglets. Degree of implementation:the methodic recommendations were published results technical provisions of Ukraine "Sodium hypochlorite solution" (TP U 24.4-00485670-047-2004). Application field: veterinary medicine.